Historical advances in cancer surgery: key milestones in the treatment of cancer

Fotografía en blanco y negro de un equipo de cirujanos realizando una operación en un quirófano, con luces brillantes iluminando el área de intervención. La imagen refleja la evolución de las técnicas quirúrgicas en la lucha contra el cáncer, destacando el papel crucial de la cirugía en el tratamiento de la enfermedad a lo largo de la historia

Cancer surgery has witnessed numerous advances over the centuries, each one marking a significant milestone in the fight against cancer. As we know, surgery is the cornerstone of cancer treatment. Therefore, on the occasion of World Cancer Day, we would like to highlight some of the most important milestones in the history of this discipline:

19th century

In 1809, Ephraim McDowell performed the first successful oophorectomy, removing a 10 kg ovarian tumor. This pioneering procedure demonstrated that it was possible to perform complex surgeries on the abdomen. It was also carried out without modern anesthesia (it did not exist at the time) or advanced sterilization techniques.

Continuing along the timeline, in 1882, Alexander von Winiwarter carried out the first palliative operation for obstructive jaundice due to pancreatic adenocarcinoma, by performing an anastomosis between the gallbladder and the colon, offering new hope for patients with biliary obstructions.

William Halsted established the anatomical principles for the treatment of breast cancer in 1894 with the development of the radical mastectomy. He designed a teardrop-shaped incision that extended along the deltopectoral groove. It also included excision of the pectoralis major muscle and incision of the pectoralis minor to allow dissection of the axillary nodes and their removal (lymphadenectomy).

20th century

In 1935, Allen Whipple described an innovative surgical procedure for treating pancreatic cancer, known as the Whipple procedure. This complex technique allowed for the resection of pancreatic tumors and improved survival rates.

In the 1940s, the introduction of radical surgery for colon and rectal cancer, developed by William Ernest Miles, marked a significant advance in the treatment of these types of cancer. Miles, a British surgeon, perfected the abdominoperineal resection technique, which involved the removal of the rectum and sigmoid colon through abdominal and perineal incisions. This approach allowed for greater removal of cancerous tissue and reduced recurrence rates.

During the 1950s, breast-conserving surgery and axillary lymphadenectomy were developed, offering less invasive and more conservative options for breast cancer patients.

The advent of laparoscopic surgery revolutionized the field of surgery in the 1970s, allowing for less invasive procedures with shorter recovery times and fewer postoperative complications.

In 1979, Dr. John Spratt performed the first hyperthermic intraperitoneal chemotherapy (HIPEC) procedure, treating a patient with peritoneal pseudomyxoma and opening up new possibilities in the treatment of abdominal cancer.

Advances in reconstructive surgery, especially in breast cancer, during the 1980s allowed patients to regain their appearance and self-esteem after cancer surgery.

Also, in 1985, a robotic platform was used for the first time on a human patient to perform neurosurgical biopsies, marking the beginning of the era of robot-assisted surgery.

21st century

In the 2000s, the introduction of robotic surgery improved the precision of surgical procedures and significantly reduced patient recovery time.

In the 2010s, advances were made in minimally invasive surgery and organ preservation techniques, improving patient outcomes and quality of life.

In 2011, Professor Marc-André Reymond performed the first pressurized intraperitoneal aerosol chemotherapy (PIPAC) procedure in Germany, offering a new treatment option for patients with peritoneal cancer.

Along the same lines, in 2016, the first electrostatically precipitated pressurized intraperitoneal aerosol chemotherapy (ePIPAC) procedure was carried out in Germany, further improving the effectiveness of the treatment.

In 2022, IVOQA performed the first procedure of ePIPAC in Spain, marking a milestone in the adoption of this innovative technique in the country.

In general, over the last decade, artificial intelligence and augmented reality have begun to be used to plan and guide cancer surgeries, taking the precision and personalization of treatment to new levels.

These milestones reflect the continuous progress and innovation in cancer surgery, significantly improving treatment options and the quality of life of patients.

From IVOQA, we want to continue contributing to these advances by joining the continuous incorporation of innovation in the treatment of cancer.

Dr. Rosa María Morera

Radiation Oncology

  • Specialist in Radiation Oncology.
  • Degree in Medicine and Surgery.  Faculty of Medicine, Complutense University of Madrid (2-8-1990).
  • Head of the Radiation Oncology Department, Hospital Universitario La Paz, Madrid.
  • Expert with university micro-credential mention in Physics, Technology and Protontherapy. King Juan Carlos University.
  • Higher University Course in Design and Management of Proton Therapy Centres. King Juan Carlos University.
  • XIX Programme of Senior Management in Health Institutions. IESE Business School. University of Navarra.
  • Master in Administration and Management of Health Services XXIV Edition (2013-2014). Pompeu Fabra University.
  • Doctoral Thesis Reading: ‘Radical thoracic irradiation and pulmonary functional study in patients with locally advanced non-small cell lung cancer. Systematic review and prospective case series’ . Qualification of outstanding ‘cum laude’.
  • Doctorate courses: Complutense University of Madrid (1995-1997).
  • She is a researcher in numerous clinical trials, publishing several national and international scientific articles.

Dr. Jose María Oliver

Breast radiology

  • Breast radiologist and specialist in cryoblation of breast lesions in the IVOQA Breast Unit.
  • Degree in Medicine and Surgery from the University of Navarra (1983-1989). Specialisation via MIR in Radiology. Number 289.
  • Specialist in radiology in several renowned hospitals, international reference and pioneer in the application of cryoablation to breast pathology in Spain.
  • Head of the Breast Radiology Section at the Hospital Universitario La Paz.
  • Member of the Spanish Society of Medical Radiology (SERAM) and the Spanish Society of Diagnostic Imaging (SEDIM).

Dr. Jesús Cañete Gómez

General and Digestive Surgery. Oncological Surgery

  • Graduate in Medicine and Surgery from the University of Seville (2000- 2006).
  • Specialist in colon and rectal cancer surgery using a minimally invasive approach.
  • Training in transanal rectal cancer treatment (TAMIS and TaTME).
    Training in minimally invasive surgery at Jackson Memorial Hospital (Miami).
  • Specialist in General Surgery at Viamed Fatima Hospital, Seville (currently).
  • Doctor of Medicine from the University of Seville (‘cum laude’).
  • Associate Professor at the University of Seville Founder of the surgical team Laparoscopic Surgery Seville – MISS (Minimally Invasive Surgical Solutions) – minimally invasive surgical techniques in scheduled and emergency surgery.
  • He has written numerous publications in journals and books and is a member of the Spanish Society of Obesity Surgery (SECO), as well as the Spanish Association of Surgeons (AEC) and the Andalusian Association of Surgeons (ASAC).

Dr. Juan José Segura Sampedro

General and digestive surgery. Oncological Surgery

  • Degree in Medicine and Surgery from the University of Seville. 2003-2009.
  • Specialist in peritoneal carinomatosis.
  • Doctor of Medicine from the University of Seville (‘cum laude’).
  • Oncological Surgeon in the Section of Peritoneal, Retroperitoneal and Soft Parts Oncological Surgery, Department of General and Digestive System Surgery, Hospital Universitario La Paz, Madrid.
  • Associate Professor of Surgery, Faculty of Medicine, University of the Balearic Islands, Palma de Mallorca.
  • 3IP in the Research Group in Advanced Oncological Surgery, m-Health and Innovation in Surgical Technology, Institute for Health Research of the Balearic Islands (IdISBa), Palma de Mallorca.
  • He has written numerous publications in journals and books and is a member of the Spanish Society of Surgical Oncology (SEOQ), the Spanish Society of Coloproctology (AECP), the Spanish Association of Surgeons (AEC), the European Society of Oncological Surgery (ESSO) and the Spanish Group of Peritoneal Oncological Surgery (GECOP).

Pablo Soto

Specialist in sports training for oncology patients

  • Higher Degree in Dietetics (2020-2022)
  • Treatment and rehabilitation of cancer patients

Dr. Gonzalez Larriba

Medical oncology

  • Professor of Medical Oncology at the Complutense University of Madrid
  • Head of the Medical Oncology Section of the Hospital Clínico San Carlos in possession of the European Certificate in Oncology
  • Recognition of 6 six-year research periods + 1 six-year period of knowledge transfer
  • Master in Oncology Services Management by the University of Alcala de Henares
  • Visiting Professor of Oncology at the University of Palermo (Italy)
  • Multiple stays in international centres (Memorial Sloan Kettering Cancer Center, Gustave Roussy Institute, University of Lyon, Princess Margaret Hospital in Toronto, University of Pittsburgh)
  • Maximum recognition of the Professional Career by the Regional Ministry of Health of the Community of Madrid
  • Director of the Master’s Degree in Genitourinary Tumours at the Complutense University of Madrid
  • Founder and member of the Board of Directors of the Spanish Lung Cancer Group, Spanish Genitourinary Tumour Group and Spanish Melanoma Group
  • Member of the Board of Directors of the Spanish Society of Medical Oncology
  • Miembro de la European Society of Medical Oncology, American Society of Clinical Oncology, International Association for the Study od Lung Cancer, etc.
  • Author of more than 300 scientific articles, 400 conference papers and 60 scientific books, as well as speaker in more than 400 conference papers

Francisco Flores

Physiotherapy

  • Graduate in physiotherapy. UEM.
  • Master’s degree in respiratory physiotherapy. UNIVERSITAT
  • ROVIRA i VIRGILI.
  • MASTER specialist in conservative and invasive physiotherapy of myofascial pain syndrome and fibromyalgia. UAH.
  • SPIROMETRIST by the ERS-SEPAR for the performance and interpretation of SPIROMETRY.
  • MASTER Specialist in intratissue percutaneous electrolysis treatments EPI.
  • Specialist in the use and application of the INDIBA ACTIV system.
  • MASTER Specialist in Biomechanical Analysis, Intervention and Treatment “Check yourMOtion”.
  • NATIONAL CLASSIFIER for athletes with cerebral palsy.
  • NATIONAL CLASSIFIER of athletics for people with physical disabilities.
  • RESEARCH PROJECT: “Respiratory physiotherapy as a treatment for ARVC in high performance athletes”.

Dr. Javier Heras Aznar

BREAST UNIT

  • Graduate in Medicine and Surgery from Universidad Autonoma de Madrid 1992.
  • Specialist via MIR in Family Medicine at Hospital Universitario Ramón y Cajal 1994-1996.
  • Specialist via MIR in OBSTETRICS AND GYNECOLOGY at Hospital Universitario Santa Cristina in Madrid 1997-2001.
  • Specialized in the last 27 years in Gynecological Oncology and Breast Pathology, both malignant and benign, with experience in Oncoplastic Surgery.
  • Specialization Course in Oncoplastic Breast Surgery 2015.
  • Coordinator of the Breast Unit and the Breast Tumors and Gynecology Oncology Committee in Hospital Universitario Infanta Sofía.
  • Main Author of the Breast Unit Accreditation Project (Hospital Universitario Infanta Sofía) 2019-2020.

Dr. Beatriz García-Conde

DIGESTIVE SYSTEM MEDICINE

  • Graduate in Medicine and Surgery.
  • MIR specialisation in Digestive System Medicine, Puerta de Hierro University Hospital in Majadahonda. Currently working at the 12 de Octubre University Hospital.
  • Specialist in capsule endoscopy and in diagnostic and therapeutic endoscopy: chromoendoscopy, colon cancer screening, digestive dilatations, PEG placement, endoluminal vacuum therapy (fistulas/leaks), polypectomy/mucosectomy.
  • She also a general digestive consultant with a Master’s Degree in Neurogastroenterology.

Dr. Micaela Riat Castro Zocchi

DIGESTIVE SYSTEM MEDICINE

  • Graduate in Medicine and Surgery.
  • MIR specialisation in Digestive System Medicine, Princesa Hospital (Madrid).
  • Clinical consultation. Diagnostic and therapeutic endoscopy: Chromoendoscopy, Colon Cancer Screening, Placement of digestive prosthesis (oesophagus, colon), Digestive dilatations, PEG Placement, Endoluminal Vacuum Therapy (fistulas/leaks), Polypectomy/mucosectomy. Experience in Bariatric Endoscopy: Intragastric balloon.

Dr. Diana Fresneda Cuesta

DIGESTIVE SYSTEM MEDICINE

  • Graduate in Medicine and Surgery.
  • MIR specialisation in Digestive System Medicine, Jiménez Díaz Foundation. (Madrid)
  • Clinical consultation. Specialist in Endoscopic Capsule and in Diagnostic and Therapeutic Endoscopy: Chromoendoscopy, Colon Cancer Screening, Ligation of Oesophagus Varices, Placement of digestive prosthesis (oesophagus, colon), Digestive dilatations, PEG Placement, Endoluminal Vacuum Therapy (fistulas/leaks), Polypectomy/mucosectomy. Experience in bariatric endoscopy: intragastric balloon, POSE method and Endo-sleeve with POSE system, etc.

Dr. Teresa Valdés Lacasa

DIGESTIVE SYSTEM MEDICINE

  • Graduate in Medicine and Surgery
  • MIR specialisation in Digestive System Medicine, 12 de Octubre University Hospital (Madrid). Advanced Endoscopy Fellowship (ERCP and digestive prostheses) at Ninewells Hospital (United Kingdom). 2020-2021.
  • Clinical consultation and abdominal ultrasound.
  • Specialist in pancreatico-biliary conditions and therapeutic endoscopy: ERCP, placement of digestive prostheses (oesophagus, duodenum, colon, biliary), digestive dilatations, placement of PEGs, endoluminal vacuum therapy (fistulas/leaks), polypectomy/mucosectomy.

Dr. Andrés J. del Pozo García, MD. PhD.

DUAL SPECIALISATION IN DIGESTIVE SYSTEM MEDICINE / FAMILY AND COMMUNITY MEDICINE

  • Graduate in Medicine and Surgery.
  • Dual specialised training (MIR) at the Princesa University Hospital (Madrid).
  • Specialist in Digestive System Medicine and Specialised in Family and Community Medicine
  • PhD in Medicine from the Autonomous University of Madrid. Cum Laude. 2020.
  • Member of S.E.P.D, S.E.E.D., A.E.G, E.S.G.E, AESPANC, Board Member of GETTEMO; Consultant of Apollo Endosurgery in 2021.

Dr. José María Abadal Villayandre

SPECIALIST IN VASCULAR INTERVENTIONAL RADIOLOGY

  • Graduate in Medicine and Surgery from Navarra University.
  • MIR specialisation in Radiology, Radiodiagnosis at Gregorio Marañón University Hospital.
  • PhD in Radiodiagnosis from the Complutense University of Madrid. Cum Laude Doctoral Thesis.
  • Specialist in Vascular Interventional Radiology, accreditation from the Spanish Society of Interventional Radiology.
  • European Board Interventional Radiology (EBIR) Health Sciences) at Alfonso X el Sabio University. 2010-2014.
  • Medical Director of the “Centro de Radiología y Diagnóstico por Imagen”.
  • Scientific and research activity with numerous publications and research studies.
  • Director and professor of Interventional Vascular Radiology at the I-XI Endo-school. Teaching activity.
  • Member of SERAM (Spanish Society of Medical Radiology), CIRSE (Cardiovascular Interventional Radiology Society Europe), and Secretary of SERVEI (Spanish Society of Interventional Vascular Radiology).

Belén Pérez Peiro. Psychologist

SPECIALIST IN PSYCHO-ONCOLOGY

  • Graduate in Psychology
  • Clinical psychologist, Gregorio Marañón University General Hospital, Psycho-oncology, Gynaecological Psychology, Neuropsychology, Detoxification and Out-patient Hospital, inflammatory bowel disease and teenagers.
  • Clinical activity at the Niño Jesús Children’s University Hospital, Psychiatric and Eating Disorder Units.
  • Expert qualification in Psychosomatic Medicine and Health Psychology.
  • Expert qualification in Psychopathology and Psychiatry from the Spanish Society of Psychosomatic Medicine and Medical Psychology.
  • Specialist qualification in Psychotherapy and projective techniques, both of which are recognised by the Madrid Official Association of Psychologists.

Dr. Ana María Moreno

SPECIALIST IN INTERNAL MEDICINE AND NUTRITIONAL PREHABILITATION

  • Graduate in Medicine and Surgery. 1986– 1992.
  • Extraordinary Graduation Award. 1992.
  • MIR specialisation in Internal Medicine. Number 283.
  • Master’s Degree in Palliative Care from Valladolid University. 2011.
  • University Master’s Degree in Advanced Chronic Nursing and palliative care from Antonio de Nebrija University. 2017.
  • PhD Courses 1993.
  • Extensive professional career in many renowned hospitals.
  • Head of Internal Medicine Services at Viamed Santa Elena (Madrid). September 2021 – Present.
  • Teaching and research work.
  • Numerous publications and papers. Participation in courses and seminars.