Colon Cancer in People Under 50: Causes Behind the Increase and How to Prevent It

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The increase in certain cases of colorectal cancer among young adults has attracted growing interest within the scientific community and has highlighted the need to strengthen prevention, early diagnosis and research strategies.

Although individual risk remains low, early detection continues to be one of the factors with the greatest impact on disease prognosis. At IVOQA (Viamed Institute of Advanced Surgical Oncology), we approach colorectal cancer from a multidisciplinary perspective, integrating advanced diagnostic techniques, highly complex oncological surgery, clinical research and personalised treatments to provide the best possible care at every stage of the patient journey.

This content has been prepared with the collaboration and review of Dr. Delia Cortés, Director of IVOQA, who has contributed her clinical expertise to ensure the accuracy and quality of the published information.

 

Colorectal cancer is no longer only a disease of older age

Colon cancer is increasing globally among younger patients due to a complex interaction between environmental factors, modern metabolic habits and genetic predisposition.

This shift in the patient profile has challenged traditional clinical patterns, making early prevention an increasingly urgent need for the active adult population.

 

What do current statistics say about early-onset colon cancer?

Epidemiological databases show a sustained increase in cases among people aged between 20 and 49 over recent decades. This shift in the age of incidence has led international scientific societies to reconsider traditional screening strategies in order to protect younger adults.

 

Why diagnosis is often delayed in younger patients

Early detection often fails because there is initially a low level of clinical suspicion among both patients themselves and primary care physicians. Early symptoms are commonly and incorrectly attributed to common benign conditions, delaying decisive diagnostic tests:

  • Haemorrhoids or anal fissures: a common cause that is often mistakenly blamed whenever rectal bleeding occurs.
  • Irritable bowel syndrome: a commonly made diagnosis when changes in bowel habits or abdominal cramps occur.
  • Food intolerances: a frequent explanation used to avoid investigating chronic difficult digestion.

 

Why are cases of colon cancer increasing among young people?

The increase in colon cancer among young people is mainly associated with the adoption of ultra-processed Western diets, prolonged sedentary lifestyles, significant alterations in the gut microbiota and undetected inherited mutations.

Identifying the factors driving this trend is the essential first step towards changing behaviours and activating clinical prevention:

  1. Lifestyle changes: Western-style diet and ultra-processed foods

Excessive consumption of processed red meat, saturated fats, refined sugars and chemical additives alters normal digestive processes. This poor-quality dietary pattern promotes a state of chronic inflammation of the intestinal mucosa that progressively damages the DNA of colon cells.

  1. The impact of sedentary lifestyles and obesity from an early age

A lack of regular physical activity slows intestinal transit, prolonging the time that waste products and toxins remain in contact with the intestinal walls. Obesity and the accumulation of adipose tissue act as metabolic disruptors that stimulate the growth of abnormal cells.

  1. Alterations in the gut microbiota

Indiscriminate use of antibiotics during childhood and chronically low-fibre diets reduce the diversity of protective gut bacteria. This intestinal dysbiosis weakens the local immune barrier of the colon, leaving it more vulnerable to carcinogenic agents.

  1. Genetic factors and family history: Lynch syndrome

Unlike sporadic cases linked to lifestyle, a proportion of early-onset tumours are related to inherited factors. Lynch syndrome and adenomatous polyposis are genetic conditions that require close monitoring from a young age in specialised units.

 

Key symptoms of colon cancer that people under 50 should not ignore

Key symptoms of colon cancer in younger people include blood in the stool, unexplained changes in bowel habits, unintentional weight loss and cramp-like abdominal pain. These symptoms are considered a warning sign when they persist for 6 weeks or more.

Learning to recognise these warning signs in your own body and visually identify them can help you consult a specialist promptly and appropriately:

  • Blood in the stool: seeing dark red blood in the toilet should never be considered normal. It is the most common and one of the most frequently misdiagnosed symptoms in young adults and should always be clinically investigated.
  • Changes in bowel habits: experiencing unusual episodes of persistent constipation, recurrent diarrhoea or noticing that stools become thin or ribbon-shaped for more than six weeks.
  • Weight loss and chronic fatigue: losing a significant amount of weight without changing your diet, accompanied by extreme tiredness caused by hidden anaemia due to microscopic blood loss.
  • Abdominal pain or cramps: experiencing a persistent feeling of pressure, painful gas or sharp pains in the lower abdomen that do not improve after a bowel movement.

Prevention, diagnosis and advanced treatment of colorectal cancer at IVOQA

At IVOQA, we approach colorectal cancer through a comprehensive strategy combining prevention, early diagnosis, highly complex oncological surgery and clinical research. Our aim is to detect the disease at its earliest stages, treat precursor lesions before they progress and offer each patient the most appropriate therapeutic option through a multidisciplinary and personalised approach.

 

Advanced colonoscopy: the standard for colorectal cancer prevention

Colonoscopy remains the reference technique for colorectal cancer prevention, as it allows polyps and other premalignant lesions to be identified and removed during the same procedure, preventing their progression into an invasive tumour.

At the Digestive Endoscopy Unit of Viamed Santa Elena University Hospital, we perform high-definition colonoscopies using advanced optical magnification and lesion characterisation technologies, improving diagnostic capability and therapeutic precision. The procedure is carried out under sedation, ensuring patient comfort and safety.

 

Non-invasive early diagnosis

In addition to colonoscopy, at IVOQA we offer non-invasive genetic stool-based early detection tests, including the Mirnax test, which can identify biomarkers associated with colorectal cancer and precursor lesions, such as polyps or advanced adenomas, before symptoms appear. These tools help identify patients who may benefit from an endoscopic evaluation and represent an important complement to screening and prevention programmes.

 

Advanced oncological surgery for colorectal cancer

When surgical treatment is indicated, our oncological surgery team uses laparoscopic and robotic techniques that allow highly precise procedures to be performed through a minimally invasive approach. These techniques are associated with reduced surgical trauma, faster functional recovery and fewer postoperative complications, while always maintaining the highest oncological quality standards.

In cases of locally advanced disease or peritoneal involvement, IVOQA also has a highly specialised unit for peritoneal carcinomatosis surgery, with access to complex procedures such as cytoreductive surgery, HIPEC, PIPAC and other locoregional therapies when indicated.

 

Structured physical exercise is part of colon cancer treatment following the results of the CHALLENGE Trial

 

A multidisciplinary committee for every patient

All cases are assessed by a Multidisciplinary Tumour Board, where oncological surgeons, medical oncologists, radiologists, pathologists, gastroenterologists, diagnostic imaging specialists, nutritionists and other professionals jointly review each clinical situation.

This care model makes it possible to design a fully individualised treatment plan based on the characteristics of the tumour, the molecular profile of the disease and the specific needs of each patient, ensuring that decisions are reached by consensus and based on the best available scientific evidence.

Research and innovation to improve outcomes

Research is part of clinical practice at IVOQA. Our institute actively participates in national and international clinical trials and develops projects aimed at incorporating new diagnostic and therapeutic strategies that provide patients with access to innovative treatments and continuously improve outcomes in colorectal oncology.

Prevention remains the best tool against colorectal cancer

Most colorectal cancers develop from precursor lesions that can be detected and treated before they progress. Therefore, participating in screening programmes, seeking medical advice when persistent digestive symptoms occur and attending check-ups when risk factors are present constitute the most effective strategy for reducing incidence and improving the prognosis of this disease.

At IVOQA, we offer patients a care model that integrates prevention, high-precision diagnosis, advanced oncological surgery, research and multidisciplinary care, with the aim of providing the most appropriate treatment at every stage of the disease.

 

Frequently asked questions about colon cancer in young adults

At what age should I start colon cancer screening if I have no symptoms?
The standard age for the general population without symptoms in Spain is 50, using the faecal occult blood test. However, if there is a direct family history of colorectal cancer or polyps, screening with advanced colonoscopy should begin at age 40 or even earlier.
Is colon cancer more aggressive in younger people?
Not necessarily because of its biological nature, but because it is often detected at more advanced stages due to the initial delay in diagnosis. When diagnostic tests are delayed because of a lack of suspicion, the tumour has more time to spread, making it appear more aggressive.
How can I request a preventive assessment consultation at the IVOQA Institute?
You can book an appointment immediately by selecting the Advanced Oncology or Digestive Diseases Unit at Viamed Santa Elena University Hospital through our online appointment website, where we will coordinate your diagnostic tests without waiting lists.
This article is for informational purposes only and does not replace diagnosis by a specialist. If you have any concerns, visit a Viamed centre.

 

 

Dr. Rosa María Morera

Radiation Oncology

  • Specialist in Radiation Oncology.
  • Degree in Medicine and Surgery.  Faculty of Medicine, Complutense University of Madrid (2-8-1990).
  • Head of the Radiation Oncology Department, Hospital Universitario La Paz, Madrid.
  • Expert with university micro-credential mention in Physics, Technology and Protontherapy. King Juan Carlos University.
  • Higher University Course in Design and Management of Proton Therapy Centres. King Juan Carlos University.
  • XIX Programme of Senior Management in Health Institutions. IESE Business School. University of Navarra.
  • Master in Administration and Management of Health Services XXIV Edition (2013-2014). Pompeu Fabra University.
  • Doctoral Thesis Reading: ‘Radical thoracic irradiation and pulmonary functional study in patients with locally advanced non-small cell lung cancer. Systematic review and prospective case series’ . Qualification of outstanding ‘cum laude’.
  • Doctorate courses: Complutense University of Madrid (1995-1997).
  • She is a researcher in numerous clinical trials, publishing several national and international scientific articles.

Dr. Jose María Oliver

Breast radiology

  • Breast radiologist and specialist in cryoblation of breast lesions in the IVOQA Breast Unit.
  • Degree in Medicine and Surgery from the University of Navarra (1983-1989). Specialisation via MIR in Radiology. Number 289.
  • Specialist in radiology in several renowned hospitals, international reference and pioneer in the application of cryoablation to breast pathology in Spain.
  • Head of the Breast Radiology Section at the Hospital Universitario La Paz.
  • Member of the Spanish Society of Medical Radiology (SERAM) and the Spanish Society of Diagnostic Imaging (SEDIM).

Dr. Jesús Cañete Gómez

General and Digestive Surgery. Oncological Surgery

  • Graduate in Medicine and Surgery from the University of Seville (2000- 2006).
  • Specialist in colon and rectal cancer surgery using a minimally invasive approach.
  • Training in transanal rectal cancer treatment (TAMIS and TaTME).
    Training in minimally invasive surgery at Jackson Memorial Hospital (Miami).
  • Specialist in General Surgery at Viamed Fatima Hospital, Seville (currently).
  • Doctor of Medicine from the University of Seville (‘cum laude’).
  • Associate Professor at the University of Seville Founder of the surgical team Laparoscopic Surgery Seville – MISS (Minimally Invasive Surgical Solutions) – minimally invasive surgical techniques in scheduled and emergency surgery.
  • He has written numerous publications in journals and books and is a member of the Spanish Society of Obesity Surgery (SECO), as well as the Spanish Association of Surgeons (AEC) and the Andalusian Association of Surgeons (ASAC).

Dr. Juan José Segura Sampedro

General and digestive surgery. Oncological Surgery

  • Degree in Medicine and Surgery from the University of Seville. 2003-2009.
  • Specialist in peritoneal carinomatosis.
  • Doctor of Medicine from the University of Seville (‘cum laude’).
  • Oncological Surgeon in the Section of Peritoneal, Retroperitoneal and Soft Parts Oncological Surgery, Department of General and Digestive System Surgery, Hospital Universitario La Paz, Madrid.
  • Associate Professor of Surgery, Faculty of Medicine, University of the Balearic Islands, Palma de Mallorca.
  • 3IP in the Research Group in Advanced Oncological Surgery, m-Health and Innovation in Surgical Technology, Institute for Health Research of the Balearic Islands (IdISBa), Palma de Mallorca.
  • He has written numerous publications in journals and books and is a member of the Spanish Society of Surgical Oncology (SEOQ), the Spanish Society of Coloproctology (AECP), the Spanish Association of Surgeons (AEC), the European Society of Oncological Surgery (ESSO) and the Spanish Group of Peritoneal Oncological Surgery (GECOP).

Pablo Soto

Specialist in sports training for oncology patients

  • Higher Degree in Dietetics (2020-2022)
  • Treatment and rehabilitation of cancer patients

Dr. Gonzalez Larriba

Medical oncology

  • Professor of Medical Oncology at the Complutense University of Madrid
  • Head of the Medical Oncology Section of the Hospital Clínico San Carlos in possession of the European Certificate in Oncology
  • Recognition of 6 six-year research periods + 1 six-year period of knowledge transfer
  • Master in Oncology Services Management by the University of Alcala de Henares
  • Visiting Professor of Oncology at the University of Palermo (Italy)
  • Multiple stays in international centres (Memorial Sloan Kettering Cancer Center, Gustave Roussy Institute, University of Lyon, Princess Margaret Hospital in Toronto, University of Pittsburgh)
  • Maximum recognition of the Professional Career by the Regional Ministry of Health of the Community of Madrid
  • Director of the Master’s Degree in Genitourinary Tumours at the Complutense University of Madrid
  • Founder and member of the Board of Directors of the Spanish Lung Cancer Group, Spanish Genitourinary Tumour Group and Spanish Melanoma Group
  • Member of the Board of Directors of the Spanish Society of Medical Oncology
  • Miembro de la European Society of Medical Oncology, American Society of Clinical Oncology, International Association for the Study od Lung Cancer, etc.
  • Author of more than 300 scientific articles, 400 conference papers and 60 scientific books, as well as speaker in more than 400 conference papers

Francisco Flores

Physiotherapy

  • Graduate in physiotherapy. UEM.
  • Master’s degree in respiratory physiotherapy. UNIVERSITAT
  • ROVIRA i VIRGILI.
  • MASTER specialist in conservative and invasive physiotherapy of myofascial pain syndrome and fibromyalgia. UAH.
  • SPIROMETRIST by the ERS-SEPAR for the performance and interpretation of SPIROMETRY.
  • MASTER Specialist in intratissue percutaneous electrolysis treatments EPI.
  • Specialist in the use and application of the INDIBA ACTIV system.
  • MASTER Specialist in Biomechanical Analysis, Intervention and Treatment “Check yourMOtion”.
  • NATIONAL CLASSIFIER for athletes with cerebral palsy.
  • NATIONAL CLASSIFIER of athletics for people with physical disabilities.
  • RESEARCH PROJECT: “Respiratory physiotherapy as a treatment for ARVC in high performance athletes”.

Dr. Javier Heras Aznar

BREAST UNIT

  • Graduate in Medicine and Surgery from Universidad Autonoma de Madrid 1992.
  • Specialist via MIR in Family Medicine at Hospital Universitario Ramón y Cajal 1994-1996.
  • Specialist via MIR in OBSTETRICS AND GYNECOLOGY at Hospital Universitario Santa Cristina in Madrid 1997-2001.
  • Specialized in the last 27 years in Gynecological Oncology and Breast Pathology, both malignant and benign, with experience in Oncoplastic Surgery.
  • Specialization Course in Oncoplastic Breast Surgery 2015.
  • Coordinator of the Breast Unit and the Breast Tumors and Gynecology Oncology Committee in Hospital Universitario Infanta Sofía.
  • Main Author of the Breast Unit Accreditation Project (Hospital Universitario Infanta Sofía) 2019-2020.

Dr. Beatriz García-Conde

DIGESTIVE SYSTEM MEDICINE

  • Graduate in Medicine and Surgery.
  • MIR specialisation in Digestive System Medicine, Puerta de Hierro University Hospital in Majadahonda. Currently working at the 12 de Octubre University Hospital.
  • Specialist in capsule endoscopy and in diagnostic and therapeutic endoscopy: chromoendoscopy, colon cancer screening, digestive dilatations, PEG placement, endoluminal vacuum therapy (fistulas/leaks), polypectomy/mucosectomy.
  • She also a general digestive consultant with a Master’s Degree in Neurogastroenterology.

Dr. Micaela Riat Castro Zocchi

DIGESTIVE SYSTEM MEDICINE

  • Graduate in Medicine and Surgery.
  • MIR specialisation in Digestive System Medicine, Princesa Hospital (Madrid).
  • Clinical consultation. Diagnostic and therapeutic endoscopy: Chromoendoscopy, Colon Cancer Screening, Placement of digestive prosthesis (oesophagus, colon), Digestive dilatations, PEG Placement, Endoluminal Vacuum Therapy (fistulas/leaks), Polypectomy/mucosectomy. Experience in Bariatric Endoscopy: Intragastric balloon.

Dr. Diana Fresneda Cuesta

DIGESTIVE SYSTEM MEDICINE

  • Graduate in Medicine and Surgery.
  • MIR specialisation in Digestive System Medicine, Jiménez Díaz Foundation. (Madrid)
  • Clinical consultation. Specialist in Endoscopic Capsule and in Diagnostic and Therapeutic Endoscopy: Chromoendoscopy, Colon Cancer Screening, Ligation of Oesophagus Varices, Placement of digestive prosthesis (oesophagus, colon), Digestive dilatations, PEG Placement, Endoluminal Vacuum Therapy (fistulas/leaks), Polypectomy/mucosectomy. Experience in bariatric endoscopy: intragastric balloon, POSE method and Endo-sleeve with POSE system, etc.

Dr. Teresa Valdés Lacasa

DIGESTIVE SYSTEM MEDICINE

  • Graduate in Medicine and Surgery
  • MIR specialisation in Digestive System Medicine, 12 de Octubre University Hospital (Madrid). Advanced Endoscopy Fellowship (ERCP and digestive prostheses) at Ninewells Hospital (United Kingdom). 2020-2021.
  • Clinical consultation and abdominal ultrasound.
  • Specialist in pancreatico-biliary conditions and therapeutic endoscopy: ERCP, placement of digestive prostheses (oesophagus, duodenum, colon, biliary), digestive dilatations, placement of PEGs, endoluminal vacuum therapy (fistulas/leaks), polypectomy/mucosectomy.

Dr. Andrés J. del Pozo García, MD. PhD.

DUAL SPECIALISATION IN DIGESTIVE SYSTEM MEDICINE / FAMILY AND COMMUNITY MEDICINE

  • Graduate in Medicine and Surgery.
  • Dual specialised training (MIR) at the Princesa University Hospital (Madrid).
  • Specialist in Digestive System Medicine and Specialised in Family and Community Medicine
  • PhD in Medicine from the Autonomous University of Madrid. Cum Laude. 2020.
  • Member of S.E.P.D, S.E.E.D., A.E.G, E.S.G.E, AESPANC, Board Member of GETTEMO; Consultant of Apollo Endosurgery in 2021.

Dr. José María Abadal Villayandre

SPECIALIST IN VASCULAR INTERVENTIONAL RADIOLOGY

  • Graduate in Medicine and Surgery from Navarra University.
  • MIR specialisation in Radiology, Radiodiagnosis at Gregorio Marañón University Hospital.
  • PhD in Radiodiagnosis from the Complutense University of Madrid. Cum Laude Doctoral Thesis.
  • Specialist in Vascular Interventional Radiology, accreditation from the Spanish Society of Interventional Radiology.
  • European Board Interventional Radiology (EBIR) Health Sciences) at Alfonso X el Sabio University. 2010-2014.
  • Medical Director of the “Centro de Radiología y Diagnóstico por Imagen”.
  • Scientific and research activity with numerous publications and research studies.
  • Director and professor of Interventional Vascular Radiology at the I-XI Endo-school. Teaching activity.
  • Member of SERAM (Spanish Society of Medical Radiology), CIRSE (Cardiovascular Interventional Radiology Society Europe), and Secretary of SERVEI (Spanish Society of Interventional Vascular Radiology).

Belén Pérez Peiro. Psychologist

SPECIALIST IN PSYCHO-ONCOLOGY

  • Graduate in Psychology
  • Clinical psychologist, Gregorio Marañón University General Hospital, Psycho-oncology, Gynaecological Psychology, Neuropsychology, Detoxification and Out-patient Hospital, inflammatory bowel disease and teenagers.
  • Clinical activity at the Niño Jesús Children’s University Hospital, Psychiatric and Eating Disorder Units.
  • Expert qualification in Psychosomatic Medicine and Health Psychology.
  • Expert qualification in Psychopathology and Psychiatry from the Spanish Society of Psychosomatic Medicine and Medical Psychology.
  • Specialist qualification in Psychotherapy and projective techniques, both of which are recognised by the Madrid Official Association of Psychologists.

Dr. Ana María Moreno

SPECIALIST IN INTERNAL MEDICINE AND NUTRITIONAL PREHABILITATION

  • Graduate in Medicine and Surgery. 1986– 1992.
  • Extraordinary Graduation Award. 1992.
  • MIR specialisation in Internal Medicine. Number 283.
  • Master’s Degree in Palliative Care from Valladolid University. 2011.
  • University Master’s Degree in Advanced Chronic Nursing and palliative care from Antonio de Nebrija University. 2017.
  • PhD Courses 1993.
  • Extensive professional career in many renowned hospitals.
  • Head of Internal Medicine Services at Viamed Santa Elena (Madrid). September 2021 – Present.
  • Teaching and research work.
  • Numerous publications and papers. Participation in courses and seminars.