Ovarian cancer: when digestive symptoms require a gynaecological assessment

Table of contents

Ovarian cancer remains one of the gynaecological cancers that is most difficult to diagnose in its early stages. Unlike other cancers, it often presents with non-specific symptoms that can be mistaken for common digestive problems, contributing to delays in diagnosis in a significant proportion of patients.

Recognising these symptoms and seeking medical advice when they persist is an important step towards achieving an earlier diagnosis and optimising treatment options.

 

Why can ovarian cancer symptoms be mistaken for a digestive problem?

The ovaries are anatomically located close to the peritoneum, bowel and bladder. Tumour growth or the presence of fluid in the abdominal cavity can cause compression and irritation of these structures, leading to digestive or urinary symptoms before specific gynaecological symptoms appear.

For this reason, many patients initially seek medical advice for persistent digestive discomfort before receiving a definitive diagnosis.

 

Symptoms that should prompt a medical assessment

Although most of these symptoms have benign causes, when they are persistent or progressive, a gynaecological assessment is recommended.

The most common warning signs include:

  • Persistent abdominal bloating or a progressive increase in abdominal circumference.
  • Feeling full quickly or reduced appetite.
  • Persistent pelvic pain or pressure.
  • Recent changes in bowel habits.
  • Increased urinary frequency or a constant urge to urinate.
  • Unintentional weight loss or persistent fatigue.

If these symptoms persist for several weeks or recur frequently, a medical assessment should be carried out to identify their cause.

 

Diagnosis of ovarian cancer

Diagnosis combines clinical information with a range of complementary tests.

Transvaginal ultrasound is the main imaging technique used for the initial assessment of ovarian masses. Depending on the findings, other investigations may be required, such as computed tomography (CT), magnetic resonance imaging (MRI) or PET-CT, to determine the extent of the disease.

Tumour markers such as CA-125 can provide additional information, although they must always be interpreted alongside the clinical examination and imaging tests, as they are not specific to ovarian cancer.

 

The approach to ovarian cancer at IVOQA

The treatment of ovarian cancer requires a highly specialised approach integrating gynaecology, oncological surgery, medical oncology, radiology, pathology and diagnostic imaging.

At IVOQA, all cases are assessed by a Multidisciplinary Tumour Board, where an individualised treatment strategy is designed taking into account the stage of the disease, tumour extent, the biological characteristics of the tumour and each patient’s clinical condition.

Highly complex oncological surgery

Surgery is one of the fundamental pillars of ovarian cancer treatment.

When the peritoneum is affected, the aim is to perform complete cytoreductive surgery, removing all visible macroscopic disease whenever technically possible. Scientific evidence has shown that the degree of cytoreduction achieved is one of the main prognostic factors in these patients.

IVOQA has a specialised peritoneal oncological surgery unit with experience in the management of advanced gynaecological tumours and highly complex procedures, including cytoreductive surgery and HIPEC when indicated.

Personalised treatment based on precision medicine

In addition to surgical treatment, the current management of ovarian cancer incorporates molecular characterisation of the tumour in order to select the most appropriate systemic therapies.

The integration of specialised surgery, chemotherapy, targeted therapies, PARP inhibitors, antiangiogenic agents, immunotherapy, ADC antibody-drug conjugates, intraperitoneal therapies when indicated and clinical research makes it possible to offer increasingly personalised treatments adapted to the characteristics of each patient, as well as emerging therapies such as drugs targeting DNA repair, vaccines and oncolytic viruses.

 

The importance of early diagnosis

Although there is currently no effective screening programme for the general population, recognising persistent symptoms and seeking a specialist assessment when they appear can help accelerate diagnosis and allow treatment to be planned at an earlier stage.

At IVOQA, we approach ovarian cancer through a care model that integrates highly complex oncological surgery, medical oncology, advanced diagnostics and clinical research, with the aim of offering each patient the most appropriate treatment strategy based on the best available scientific evidence.

 

 

Frequently asked questions about ovarian cancer symptoms

Can ovarian cancer be detected with a routine smear test?
No. A routine cervical smear test is designed exclusively to detect premalignant lesions of the cervix. To identify abnormalities in the ovaries, an additional transvaginal ultrasound is essential.
Which doctor should I see if I have these persistent symptoms?
If the digestive symptoms described last for more than three weeks and do not improve with treatment from your GP, the main recommendation is to see a gynaecologist directly in order to safely rule out a pelvic cause.
Why is IVOQA a referral centre for the treatment of advanced ovarian cancer?
We are a referral centre because we have a specialised Peritoneal Oncological Surgery Unit at Viamed Santa Elena Hospital, equipped with the technology required to perform extensive tumour resections, administer intraperitoneal therapies and provide immediate multidisciplinary support.
This article is for informational purposes only and does not replace diagnosis by a specialist. If you have any concerns, visit a Viamed centre.

Dr. Rosa María Morera

Radiation Oncology

  • Specialist in Radiation Oncology.
  • Degree in Medicine and Surgery.  Faculty of Medicine, Complutense University of Madrid (2-8-1990).
  • Head of the Radiation Oncology Department, Hospital Universitario La Paz, Madrid.
  • Expert with university micro-credential mention in Physics, Technology and Protontherapy. King Juan Carlos University.
  • Higher University Course in Design and Management of Proton Therapy Centres. King Juan Carlos University.
  • XIX Programme of Senior Management in Health Institutions. IESE Business School. University of Navarra.
  • Master in Administration and Management of Health Services XXIV Edition (2013-2014). Pompeu Fabra University.
  • Doctoral Thesis Reading: ‘Radical thoracic irradiation and pulmonary functional study in patients with locally advanced non-small cell lung cancer. Systematic review and prospective case series’ . Qualification of outstanding ‘cum laude’.
  • Doctorate courses: Complutense University of Madrid (1995-1997).
  • She is a researcher in numerous clinical trials, publishing several national and international scientific articles.

Dr. Jose María Oliver

Breast radiology

  • Breast radiologist and specialist in cryoblation of breast lesions in the IVOQA Breast Unit.
  • Degree in Medicine and Surgery from the University of Navarra (1983-1989). Specialisation via MIR in Radiology. Number 289.
  • Specialist in radiology in several renowned hospitals, international reference and pioneer in the application of cryoablation to breast pathology in Spain.
  • Head of the Breast Radiology Section at the Hospital Universitario La Paz.
  • Member of the Spanish Society of Medical Radiology (SERAM) and the Spanish Society of Diagnostic Imaging (SEDIM).

Dr. Jesús Cañete Gómez

General and Digestive Surgery. Oncological Surgery

  • Graduate in Medicine and Surgery from the University of Seville (2000- 2006).
  • Specialist in colon and rectal cancer surgery using a minimally invasive approach.
  • Training in transanal rectal cancer treatment (TAMIS and TaTME).
    Training in minimally invasive surgery at Jackson Memorial Hospital (Miami).
  • Specialist in General Surgery at Viamed Fatima Hospital, Seville (currently).
  • Doctor of Medicine from the University of Seville (‘cum laude’).
  • Associate Professor at the University of Seville Founder of the surgical team Laparoscopic Surgery Seville – MISS (Minimally Invasive Surgical Solutions) – minimally invasive surgical techniques in scheduled and emergency surgery.
  • He has written numerous publications in journals and books and is a member of the Spanish Society of Obesity Surgery (SECO), as well as the Spanish Association of Surgeons (AEC) and the Andalusian Association of Surgeons (ASAC).

Dr. Juan José Segura Sampedro

General and digestive surgery. Oncological Surgery

  • Degree in Medicine and Surgery from the University of Seville. 2003-2009.
  • Specialist in peritoneal carinomatosis.
  • Doctor of Medicine from the University of Seville (‘cum laude’).
  • Oncological Surgeon in the Section of Peritoneal, Retroperitoneal and Soft Parts Oncological Surgery, Department of General and Digestive System Surgery, Hospital Universitario La Paz, Madrid.
  • Associate Professor of Surgery, Faculty of Medicine, University of the Balearic Islands, Palma de Mallorca.
  • 3IP in the Research Group in Advanced Oncological Surgery, m-Health and Innovation in Surgical Technology, Institute for Health Research of the Balearic Islands (IdISBa), Palma de Mallorca.
  • He has written numerous publications in journals and books and is a member of the Spanish Society of Surgical Oncology (SEOQ), the Spanish Society of Coloproctology (AECP), the Spanish Association of Surgeons (AEC), the European Society of Oncological Surgery (ESSO) and the Spanish Group of Peritoneal Oncological Surgery (GECOP).

Pablo Soto

Specialist in sports training for oncology patients

  • Higher Degree in Dietetics (2020-2022)
  • Treatment and rehabilitation of cancer patients

Dr. Gonzalez Larriba

Medical oncology

  • Professor of Medical Oncology at the Complutense University of Madrid
  • Head of the Medical Oncology Section of the Hospital Clínico San Carlos in possession of the European Certificate in Oncology
  • Recognition of 6 six-year research periods + 1 six-year period of knowledge transfer
  • Master in Oncology Services Management by the University of Alcala de Henares
  • Visiting Professor of Oncology at the University of Palermo (Italy)
  • Multiple stays in international centres (Memorial Sloan Kettering Cancer Center, Gustave Roussy Institute, University of Lyon, Princess Margaret Hospital in Toronto, University of Pittsburgh)
  • Maximum recognition of the Professional Career by the Regional Ministry of Health of the Community of Madrid
  • Director of the Master’s Degree in Genitourinary Tumours at the Complutense University of Madrid
  • Founder and member of the Board of Directors of the Spanish Lung Cancer Group, Spanish Genitourinary Tumour Group and Spanish Melanoma Group
  • Member of the Board of Directors of the Spanish Society of Medical Oncology
  • Miembro de la European Society of Medical Oncology, American Society of Clinical Oncology, International Association for the Study od Lung Cancer, etc.
  • Author of more than 300 scientific articles, 400 conference papers and 60 scientific books, as well as speaker in more than 400 conference papers

Francisco Flores

Physiotherapy

  • Graduate in physiotherapy. UEM.
  • Master’s degree in respiratory physiotherapy. UNIVERSITAT
  • ROVIRA i VIRGILI.
  • MASTER specialist in conservative and invasive physiotherapy of myofascial pain syndrome and fibromyalgia. UAH.
  • SPIROMETRIST by the ERS-SEPAR for the performance and interpretation of SPIROMETRY.
  • MASTER Specialist in intratissue percutaneous electrolysis treatments EPI.
  • Specialist in the use and application of the INDIBA ACTIV system.
  • MASTER Specialist in Biomechanical Analysis, Intervention and Treatment “Check yourMOtion”.
  • NATIONAL CLASSIFIER for athletes with cerebral palsy.
  • NATIONAL CLASSIFIER of athletics for people with physical disabilities.
  • RESEARCH PROJECT: “Respiratory physiotherapy as a treatment for ARVC in high performance athletes”.

Dr. Javier Heras Aznar

BREAST UNIT

  • Graduate in Medicine and Surgery from Universidad Autonoma de Madrid 1992.
  • Specialist via MIR in Family Medicine at Hospital Universitario Ramón y Cajal 1994-1996.
  • Specialist via MIR in OBSTETRICS AND GYNECOLOGY at Hospital Universitario Santa Cristina in Madrid 1997-2001.
  • Specialized in the last 27 years in Gynecological Oncology and Breast Pathology, both malignant and benign, with experience in Oncoplastic Surgery.
  • Specialization Course in Oncoplastic Breast Surgery 2015.
  • Coordinator of the Breast Unit and the Breast Tumors and Gynecology Oncology Committee in Hospital Universitario Infanta Sofía.
  • Main Author of the Breast Unit Accreditation Project (Hospital Universitario Infanta Sofía) 2019-2020.

Dr. Beatriz García-Conde

DIGESTIVE SYSTEM MEDICINE

  • Graduate in Medicine and Surgery.
  • MIR specialisation in Digestive System Medicine, Puerta de Hierro University Hospital in Majadahonda. Currently working at the 12 de Octubre University Hospital.
  • Specialist in capsule endoscopy and in diagnostic and therapeutic endoscopy: chromoendoscopy, colon cancer screening, digestive dilatations, PEG placement, endoluminal vacuum therapy (fistulas/leaks), polypectomy/mucosectomy.
  • She also a general digestive consultant with a Master’s Degree in Neurogastroenterology.

Dr. Micaela Riat Castro Zocchi

DIGESTIVE SYSTEM MEDICINE

  • Graduate in Medicine and Surgery.
  • MIR specialisation in Digestive System Medicine, Princesa Hospital (Madrid).
  • Clinical consultation. Diagnostic and therapeutic endoscopy: Chromoendoscopy, Colon Cancer Screening, Placement of digestive prosthesis (oesophagus, colon), Digestive dilatations, PEG Placement, Endoluminal Vacuum Therapy (fistulas/leaks), Polypectomy/mucosectomy. Experience in Bariatric Endoscopy: Intragastric balloon.

Dr. Diana Fresneda Cuesta

DIGESTIVE SYSTEM MEDICINE

  • Graduate in Medicine and Surgery.
  • MIR specialisation in Digestive System Medicine, Jiménez Díaz Foundation. (Madrid)
  • Clinical consultation. Specialist in Endoscopic Capsule and in Diagnostic and Therapeutic Endoscopy: Chromoendoscopy, Colon Cancer Screening, Ligation of Oesophagus Varices, Placement of digestive prosthesis (oesophagus, colon), Digestive dilatations, PEG Placement, Endoluminal Vacuum Therapy (fistulas/leaks), Polypectomy/mucosectomy. Experience in bariatric endoscopy: intragastric balloon, POSE method and Endo-sleeve with POSE system, etc.

Dr. Teresa Valdés Lacasa

DIGESTIVE SYSTEM MEDICINE

  • Graduate in Medicine and Surgery
  • MIR specialisation in Digestive System Medicine, 12 de Octubre University Hospital (Madrid). Advanced Endoscopy Fellowship (ERCP and digestive prostheses) at Ninewells Hospital (United Kingdom). 2020-2021.
  • Clinical consultation and abdominal ultrasound.
  • Specialist in pancreatico-biliary conditions and therapeutic endoscopy: ERCP, placement of digestive prostheses (oesophagus, duodenum, colon, biliary), digestive dilatations, placement of PEGs, endoluminal vacuum therapy (fistulas/leaks), polypectomy/mucosectomy.

Dr. Andrés J. del Pozo García, MD. PhD.

DUAL SPECIALISATION IN DIGESTIVE SYSTEM MEDICINE / FAMILY AND COMMUNITY MEDICINE

  • Graduate in Medicine and Surgery.
  • Dual specialised training (MIR) at the Princesa University Hospital (Madrid).
  • Specialist in Digestive System Medicine and Specialised in Family and Community Medicine
  • PhD in Medicine from the Autonomous University of Madrid. Cum Laude. 2020.
  • Member of S.E.P.D, S.E.E.D., A.E.G, E.S.G.E, AESPANC, Board Member of GETTEMO; Consultant of Apollo Endosurgery in 2021.

Dr. José María Abadal Villayandre

SPECIALIST IN VASCULAR INTERVENTIONAL RADIOLOGY

  • Graduate in Medicine and Surgery from Navarra University.
  • MIR specialisation in Radiology, Radiodiagnosis at Gregorio Marañón University Hospital.
  • PhD in Radiodiagnosis from the Complutense University of Madrid. Cum Laude Doctoral Thesis.
  • Specialist in Vascular Interventional Radiology, accreditation from the Spanish Society of Interventional Radiology.
  • European Board Interventional Radiology (EBIR) Health Sciences) at Alfonso X el Sabio University. 2010-2014.
  • Medical Director of the “Centro de Radiología y Diagnóstico por Imagen”.
  • Scientific and research activity with numerous publications and research studies.
  • Director and professor of Interventional Vascular Radiology at the I-XI Endo-school. Teaching activity.
  • Member of SERAM (Spanish Society of Medical Radiology), CIRSE (Cardiovascular Interventional Radiology Society Europe), and Secretary of SERVEI (Spanish Society of Interventional Vascular Radiology).

Belén Pérez Peiro. Psychologist

SPECIALIST IN PSYCHO-ONCOLOGY

  • Graduate in Psychology
  • Clinical psychologist, Gregorio Marañón University General Hospital, Psycho-oncology, Gynaecological Psychology, Neuropsychology, Detoxification and Out-patient Hospital, inflammatory bowel disease and teenagers.
  • Clinical activity at the Niño Jesús Children’s University Hospital, Psychiatric and Eating Disorder Units.
  • Expert qualification in Psychosomatic Medicine and Health Psychology.
  • Expert qualification in Psychopathology and Psychiatry from the Spanish Society of Psychosomatic Medicine and Medical Psychology.
  • Specialist qualification in Psychotherapy and projective techniques, both of which are recognised by the Madrid Official Association of Psychologists.

Dr. Ana María Moreno

SPECIALIST IN INTERNAL MEDICINE AND NUTRITIONAL PREHABILITATION

  • Graduate in Medicine and Surgery. 1986– 1992.
  • Extraordinary Graduation Award. 1992.
  • MIR specialisation in Internal Medicine. Number 283.
  • Master’s Degree in Palliative Care from Valladolid University. 2011.
  • University Master’s Degree in Advanced Chronic Nursing and palliative care from Antonio de Nebrija University. 2017.
  • PhD Courses 1993.
  • Extensive professional career in many renowned hospitals.
  • Head of Internal Medicine Services at Viamed Santa Elena (Madrid). September 2021 – Present.
  • Teaching and research work.
  • Numerous publications and papers. Participation in courses and seminars.