{"id":7306,"date":"2025-04-09T13:27:59","date_gmt":"2025-04-09T13:27:59","guid":{"rendered":"https:\/\/www.viamedsalud.com\/ivoqa\/?p=7306"},"modified":"2025-04-09T13:28:09","modified_gmt":"2025-04-09T13:28:09","slug":"treatment-of-liver-metastases-current-options-and-innovative-advances","status":"publish","type":"post","link":"https:\/\/www.viamedsalud.com\/ivoqa\/en\/disease\/liver-cancer\/treatment-of-liver-metastases-current-options-and-innovative-advances\/","title":{"rendered":"Treatment of liver metastases: current options and innovative advances"},"content":{"rendered":"

Hepatic metastases<\/strong> develop when cancer cells from a primary tumour in another part of the body, such as the colon, pancreas or lungs, spread and lodge in the liver. Since the liver acts as a filter for blood from the digestive system, it is especially vulnerable to this spread.<\/p>\n

This type of metastasis represents one of the most complex challenges in oncology. However, thanks to medical and technological advances, there are now multiple strategies that not only prolong life, but also significantly improve the quality of life of patients.<\/p>\n

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Treatment options for liver metastases<\/strong><\/h2>\n

Liver surgery or surgical resection<\/strong><\/a><\/h3>\n

When metastases are limited in number and size, and the patient maintains good liver function, surgical resection<\/strong> may be an option. This procedure consists of removing the affected areas of the liver with safety margins.<\/p>\n

The surgery offers great benefits in selected patients<\/strong>, and can even lead to prolonged remission or potentially a cure in certain cases.<\/p>\n

At IVOQA we have hepatobiliary surgeons who are experts in robotic and laparoscopic liver surgery.<\/p>\n

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Radiofrequency ablation and cryoablation<\/strong><\/h3>\n

For patients who are not surgical candidates or for patients for whom this option is chosen in order to minimise surgical aggression, there are minimally invasive<\/strong> techniques such as radiofrequency ablation<\/strong><\/a>, which destroys tumours using heat, or cryoablation<\/strong>, which uses extreme cold.<\/p>\n

These techniques are carried out using image-guided needles and are effective on small lesions, with fewer side effects and shorter recovery times than conventional surgery.<\/p>\n

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Systemic chemotherapy<\/strong><\/h3>\n

Chemotherapy is<\/strong> still one of the fundamental pillars of treatment. It acts not only on liver metastases, but also on the primary tumour and other possible disseminations.<\/p>\n

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Transarterial chemoembolisation<\/a> (TACE)<\/strong><\/h3>\n

Chemoembolisation, also known as transarterial chemoembolisation (TACE), is a procedure that combines the administration of chemotherapy with embolisation to treat tumours, mainly in the liver and liver metastases.<\/p>\n

Chemoembolisation focuses a large dose of chemotherapy directly on a tumour, reducing the blood supply to the tumour and causing it to shrink.<\/p>\n

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Targeted therapies and immunotherapy<\/strong><\/h3>\n

Targeted therapies<\/strong> block specific molecules necessary for tumour cell growth. Examples include EGFR inhibitors and antiangiogenics such as bevacizumab<\/strong><\/a>.<\/p>\n

Immunotherapy<\/strong>, on the other hand, stimulates the immune system to recognise and destroy cancer cells. Drugs such as nivolumab or pembrolizumab<\/strong> have been shown to be effective in certain types of metastatic cancer, including liver cancer.<\/p>\n

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Innovative advances in the treatment of liver metastases<\/strong><\/h2>\n

In recent years, new technologies<\/strong> have emerged that are revolutionising treatment. One of them is stereotactic body radiotherapy (SBRT)<\/strong>, capable of treating metastases with great precision and minimal damage to healthy tissue.<\/p>\n

In addition, clinical trials and experimental therapies<\/strong> are underway, offering new hope through cell therapies, therapeutic vaccines and innovative drug combinations.<\/p>\n

Constant research is key to further expanding the options and personalising the treatment for each patient.<\/p>\n

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Factors influencing the choice of treatment<\/strong><\/h2>\n

The ideal treatment varies according to multiple factors, including:<\/p>\n